Perinatal Outcomes of Small for Gestational Age Infants in a Korean Tertiary Medical Center |
Hyun Sun Ko1, Rayon Kim2, Jae Yeong Park2, Yu Ri Jang2, In Yang
Park2, Jong Chul Shin2 |
1Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea 2Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea |
단일 3차 의료기관에서 부당 경량 출생아 들의 주산기 예후 |
고현선1, 김라연2, 박재영2, 장유리2, 박인양2, 신종철2 |
1가톨릭대학교 2가톨릭대학교 의과대학 서울성모병원 산부인과 |
Correspondence:
In Yang
Park, Email: ooooobbbbb@catholic.ac.kr |
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Abstract |
Purpose To examine the perinatal outcomes of small for gestational age (SGA) infants, compared with non- SGA infants and those born at 39 weeks, and to determine the optimal gestational age of delivery Methods: We performed a retrospective cohort study (n=7,580) for births at a tertiary hospital. SGA was stratified into severe (below 5th percentile) and moderate (5~10th percentile) groups. Statistical comparison was performed using the χ2 test and multivariable logistic regression models.
Results As compared to the non-SGA group at 38 weeks’ births, the odds of sepsis were significantly increased in the moderate SGA group (OR 2.84, 95% CI, 1.12~7.20) and severe SGA group (OR 3.63, 95% CI, 1.14~11.58). In addition, the odds of respiratory distress syndrome at 41 weeks’ births were significantly increased in moderate SGA (OR 15.32, 95% CI, 1.92~122.08) and severe SGA (OR 16.31, 95% CI, 1.18~226.14) groups, compared to it in the non-SGA group. The odds of other neonatal outcomes in the moderate SGA group were not significantly increased, as compared to the non-SGA group. However, the odds of neonatal intensive care unit admission and composite morbidity in the severe SGA group were significantly increased at 35, 36, 38, 39, 40, and 41 weeks’ births, as compared to the non-SGA group. There was no significant difference in neonatal outcomes from 38 to 41 weeks in moderate SGA, and from 37 to 41 weeks in severe SGA.
Conclusion If there is no medical indication, delivery at 39 weeks can be considered in SGA pregnancies. However, delivery can be planned from 37 gestational weeks in severe SGA pregnancies,with a subjective finding of fetal compromise. |
Key Words:
small for gestational age, neonatal, morbidity, delivery |
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