| Understanding of Human Embryo Development for Teratogen Counselling |
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Yikyeong Chun1, Heechul Lee2 |
1Department of Pathology, Cheil General Hospital and Women's Healthcare Center, Dankook University School of Medicine, Seoul, Korea
2Department of Pediatrics, Cheil General Hospital and Women's Healthcare Center, Dankook University School of Medicine, Seoul, Korea |
| 기형유발물질 상담을 위한 인간배아발생의 이해 |
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전이경1, 이희철2 |
1단국대학교 의과대학 제일병원 병리과
2단국대학교 의과대학 제일병원 소아청소년과 |
Correspondence:
Heechul Lee,
Email: lorjeslee@gmail.com
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| Abstract |
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Human embryology is the study of development from a single cell to a baby in 9 months. Implantation occurs at the end of the first week of development. The second week of development is known as the week of 2’s. Gastrulation, the most characteristic event occurring in the third week, establishes three germ layers composed of ectoderm, mesoderm, and endoderm. The three germ layers and neural crest cells lead to the development of their own tissues and organs during the embryonic period, which extends from the third to the eighth week. Major congenital malformations occur in the embryonic period. The fetal period, from the third month to the day of birth, is the time for maturation of tissues and organs, and growth of the body. Because of the close relationship between embryology and congenital abnormalities, knowledge of human development is essential to assess the effects on the embryo when the mother has been exposed to teratogens. This paper briefly reviews the normal embryonic development and associated congenital malformation. |
| Key Words:
embryology, neural crest, congenital abnormalities, gastrulation, neurulation |
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